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1W0C:
Inhibition of Leishmania major pteridine reductase (PTR1) by 2,4,6-triaminoquinazoline; structure of the NADP ternary complex
PDB ID:
1W0C
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MMDB ID:
29687
PDB Deposition Date:
2004/6/2
Updated in MMDB:
2023/12
Experimental Method:
x-ray diffraction
Resolution:
2.6 Å
Source Organism:
Leishmania major
Similar Structures:
VAST+
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Biological Unit for 1W0C: tetrameric; determined by author and by software (PQS)
Molecular Components in 1W0C
Label
Count
Molecule
Proteins (4 molecules)
A
B
C
D
4
Pteridine Reductase
Chemicals and Non-standard biopolymers (9 molecules)
1
4
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
5
2,4,6-TRIAMINOQUINAZOLINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303